"Immortality Herb" becoming more popular as an ADAPTOGEN - providing stress relief and immune modulation
By ljdevon // 2025-04-04
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In the world of herbal remedies, ginseng and ginkgo biloba have long held the spotlight for their cognitive and energy-boosting properties. However, a lesser-known herb is quietly gaining attention for its potential to revolutionize health and longevity. Meet jiaogulan, the so-called "immortality herb" that is capturing the interest of researchers and health enthusiasts alike.

The rise of Jiaogulan: an adaptogen

Jiaogulan, officially known as Gynostemma pentaphyllum and colloquially as "southern ginseng" or "miracle grass," has been a staple in traditional Asian medicine for centuries. This unassuming vine, native to the mountainous and forested regions of Asia, is now being hailed as a powerhouse of health benefits. Despite its growing popularity, Dr. Michael Aziz, a New York City-based internist and regenerative medicine specialist, notes that "few people in the US know about it." Dr. Aziz, who incorporates 900 milligrams of jiaogulan into his daily routine, is a strong advocate for the herb. He emphasizes its potential to increase metabolism, lower cholesterol, and reduce inflammation, all while promoting longevity.

The science behind the herb

Jiaogulan's health benefits are largely attributed to its rich content of gypenosides, a type of saponin. These compounds are structurally similar to the ginsenosides found in ginseng but are even more abundant in jiaogulan, with over 80 unique saponins identified. According to Dr. Aziz, gypenosides "stimulate AMP-activated protein kinase, an enzyme that plays a central role in maintaining cellular energy balance and has antioxidant effects." These gypenosides also improve insulin signaling and enhance mitochondrial function, which are crucial for cellular energy production and overall health. "Those are some of the hallmarks of aging that affect longevity," Dr. Aziz explains.

Health benefits

1. Heart health and blood pressure regulation: Jiaogulan has been shown to improve circulation and support healthy blood pressure. A study published in the Journal of Human Hypertension found that participants taking jiaogulan extract experienced significant reductions in blood pressure. 2. Adaptogenic stress relief: Like other adaptogens such as ashwagandha and rhodiola, jiaogulan helps the body adapt to stress by regulating cortisol levels. Research published in Phytomedicine highlighted its potential to reduce fatigue and improve mental clarity. 3. Antioxidant and anti-aging effects: The activation of the AMPK enzyme by jiaogulan is linked to cellular repair and longevity. Its high antioxidant content may combat oxidative stress, a key factor in aging and chronic disease. 4. Blood sugar support: Preliminary studies suggest that jiaogulan may enhance insulin sensitivity, making it a promising adjunct for metabolic health. A 2020 review in Frontiers in Pharmacology underscored its potential in this area. 5. Immune system modulation: Jiaogulan's polysaccharides may stimulate immune function, as evidenced by animal studies where it increased white blood cell activity.

Consumption and safety

Jiaogulan is primarily consumed as a tea or in dietary supplements. Dr. Aziz recommends brewing one to two teaspoons of dried jiaogulan leaves in 250 milliliters of water, straining, and serving. The taste is described as bitter but slightly sweet, with an "earthy" quality. While generally considered safe, jiaogulan can cause side effects such as nausea, diarrhea, dizziness, blurred vision, or tinnitus. People taking medications should consult with a healthcare provider before adding jiaogulan to their routine, as it can interact with certain drugs. Diabetics, in particular, should be cautious, as jiaogulan can lower blood sugar levels. Dosage & Preparation • Tea: 2–3 grams of dried leaves steeped in hot water, 1–3 times daily. • Extract/Tincture: 30–60 drops (1–2 mL) of a 1:5 extract, 1–3 times daily. • Capsules: 500–1,000 mg standardized extract, 1–2 times daily.

A promising future

As research into jiaogulan continues to expand, this "immortality herb" is poised to become a staple in the world of natural health. Its potential to enhance longevity, support heart health, and provide adaptogenic stress relief makes it a compelling addition to any wellness regimen. Similar Adaptogenic Herbs • Ashwagandha (Withania somnifera) – Stress relief, energy • Rhodiola (Rhodiola rosea) – Fatigue reduction, cognitive support • Holy Basil (Ocimum sanctum) – Anti-anxiety, metabolic health • Reishi Mushroom (Ganoderma lucidum) – Immune modulation, longevity In the words of Dr. Aziz, "Jiaogulan is a remarkable herb that deserves more attention in the West. Its health benefits are backed by science, and its potential is truly exciting." As more people discover the wonders of jiaogulan, it may soon rival popular adaptogenic herbs as a go-to herbal remedy for modern health challenges. Sources include: NYPost.com ScienceDirect.com Enoch, Brighteon.ai
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